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Solifenacin immediate-release Tablets

 
Maximum Quantity Allowed:
5 mg
10 mg
30 tablets
£

Solifenacin is a medication known as an antimuscarinic or anticholinergic that is used to treat overactive bladder symptoms. 

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Description

The active substance of Solifenacin belongs to the group of anticholinergics. These medicines are used to
reduce the activity of an overactive bladder. This enables you to wait longer before having to go to the bathroom and increases the amount of urine that can be held by your bladder.

Solifenacin is used to treat the symptoms of a condition called overactive bladder. These symptoms include:
having a strong, sudden urge to urinate without prior warning, having to urinate frequently or wetting yourself because you could not get to the bathroom in time.

Warnings

Talk to your doctor or pharmacist before taking Solifenacin if you

  • have trouble emptying your bladder (= bladder obstruction) or have difficulty in passing urine (e.g. a thin urine flow). Risk of accumulation of urine in the bladder (urinary retention) is much higher.
  • have some obstruction of the digestive system (constipation).
  • are at risk of your digestive system slowing down (stomach and bowel movements). Your doctor will have informed you if this is the case.
  • suffer from severe kidney disease.
  • have moderate liver disease.
  • are being treated with medicines that may decrease the removal of solifenacin from the body (for example, ketoconazole).
  • have a stomach tear (hiatus hernia) or heartburn.
  • have a nervous disorder (autonomic neuropathy).

Inform your doctor if you have or ever had any of the above mentioned conditions before treatment with
solifenacin starts.

Before starting solifenacin, your doctor will assess whether there are other causes for your need to pass urine frequently (for example heart failure (insufficient pumping power of the heart) or kidney disease). If you have a urinary tract infection, your doctor will prescribe you an antibiotic (a treatment against particular bacterial infections).

Directions

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or
pharmacist if you are not sure.


The usual dose is 5 mg per day, unless your doctor told you to take 10 mg per day.

Try to take solifenacin at the same time each day.

Solifenacin must be swallowed whole with a drink. It can be taken with or without food, according to your
preference. Do not crush the tablets.

Talk to your doctor or pharmacist if you have the impression that the effect of solifenacin is too strong or too weak.

Ingredients

The active substance is solifenacin succinate.

 Solifenacin 5 mg: Each tablet contains 5 mg solifenacin succinate, corresponding to 3.8 mg solifenacin.
 

Solifenacin 10 mg: Each tablet contains 10 mg solifenacin succinate, corresponding to 7.5 mg solifenacin.

The other ingredients are:

Core tablet: Maize starch pregelatinized; lactose monohydrate; cellulose, microcrystalline; hypromellose; magnesium stearate.

Film coating: Macrogol 6000; talc; hypromellose; titanium dioxide (E171); Iron oxide yellow (E172) - Solifenacin 5 mg; Iron oxide red (E172) - Solifenacin 10 mg

Side Effects

Very common (may affect more than 1 in 10 people):


•     Dry mouth.

Common (may affect up to 1 in 10 people):

•     Blurred vision.
•     Constipation; nausea; indigestion with symptoms such as abdominal fullness, abdominal pain, burping and heartburn (dyspepsia), stomach discomfort.

Uncommon (may affect up to 1 in 100 people):

•     Urinary tract infections; bladder infection (cystitis).
•     Sleepiness; impaired sense of taste (dysgeusia).
•     Dry (irritated) eyes.
•     Dry nasal passages.
•     Reflux disease (gastro-oesophageal reflux); dry throat.
•     Dry skin.
•     Difficulty in passing urine.
•     Fatigue, swelling of the lower limbs (oedema).

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