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Zyban tablets to aid with smoking cessation

 
Maximum Quantity Allowed:
150mg
60 prolonged-release tablets
£

Zyban is a medicine prescribed to help you stop smoking, when you also have motivational support such as taking part in a ‘stop smoking’ programme.


Zyban will be most effective if you are fully committed to giving up smoking. Ask your doctor or pharmacist for advice on treatments and other support to help you stop.

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Description

This medication is used in combination with a stop-smoking program (such as a support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (such as irritability, anxiety, restlessness) and your urge to smoke.

Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain.

Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.

Warnings

Don’t take Zyban:

  •  if you are allergic to bupropion or any of the other ingredients of this medicine 
  • if you are taking any other medicines which contain bupropion
  • if you have a condition that causes fits (seizures), such as epilepsy, or if you have a history of fits
  • if you have an eating disorder or had one in the past (for example, bulimia or anorexia nervosa)
  • if you have severe liver problems, such as cirrhosis
  • if you have a brain tumour
  • if you are usually a heavy drinker and you have just stopped drinking alcohol, or are going to stop
  • while you’re taking Zyban
  • if you have recently stopped taking sedatives or medicines to treat anxiety (especially benzodiazepines or similar medicines), or if you are going to stop them while you’re taking Zyban
  • if you have a bipolar disorder (extreme mood swings) as Zyban could bring on an episode of this illness
  • if you are taking medicines for depression or Parkinson’s disease called monoamine oxidase inhibitors (MAOIs), or have taken them in the last 14 days. The timing may be shorter for some types of MAOIs, your doctor will advise you.
  • If any of these applies to you, talk to your doctor straight away, and don’t take Zyban.

Directions

Always take this medicine exactly as your doctor or pharmacist has told you. Check with your
doctor or pharmacist if you are not sure.

Ingredients

Each tablet contains 150 mg of the active substance, bupropion hydrochloride.

The other ingredients are:

Tablet core; microcrystalline cellulose, hypromellose, cysteine hydrochloride monohydrate, magnesium stearate.

Tablet coating; hypromellose, macrogol 400, titanium dioxide (E171), carnauba wax. Printing ink; hypromellose, iron oxide black (E172).

Side Effects

Very common side effects
These may affect more than one in 10 people:

  • difficulty in sleeping (make sure you don’t take Zyban near to bedtime).

Common side effects
These may affect up to one in 10 people:

  • feeling depressed (see also ‘Warnings and Precautions’ in section 2)
  • feeling anxious or agitated
  • difficulty concentrating
  • feeling shaky (tremor)
  • headache
  • feeling sick (nausea), being sick (vomiting)
  • stomach pain or other upsets (such as constipation), changes in the taste of food, dry mouth
  • fever, dizziness, sweating, skin rash (sometimes due to an allergic reaction), itching.

Uncommon side effects
These may affect up to one in 100 people:

  • ringing in the ears, visual disturbances
  • increase in blood pressure (sometimes severe), flushing
  • loss of appetite (anorexia)
  • feeling weak
  • chest pain
  • feeling confused
  • rapid heartbeat.

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