Top Trending Weight Loss Medications in 2024

Top Trending Weight Loss Medications in 2024

18 / Dec

According to UK Health Media, Obesity is a big problem for the NHS in the UK, costing them about £6.5 billion every year. It’s also the second leading cause of cancer that can be prevented. In England, more than one in four adults (26%) and nearly a quarter of children aged 10-11 (23.4%) have obesity.

Sometimes, people struggle to lose weight even with a healthy diet and exercise. They often have trouble controlling their hunger due to various reasons. That’s why healthcare professionals prescribe weight loss medications to treat obesity along with a calorie deficit diet. 

In this blog, you will learn about the top-trending weight loss medications in the UK, insights into their effectiveness and safety, and how they can help you in your weight loss journey.

Understanding Weight Loss Medications

Weight loss medications are not just supplements; they are scientifically formulated drugs designed to treat chronic weight management. These medications work through various mechanisms, such as suppressing appetite, increasing metabolism, or preventing fat absorption. 

Effects of weight loss medications on human body.

How Do Weight Loss Medications Work?

These medications control hormones in the brain, gut, and fat cells to reduce hunger and cravings and make you feel full.

Research indicates that weight loss medicines are only effective when combined with the proper lifestyle adjustments while supported by qualified healthcare professionals.

You can take some as pills or get them as injections under the skin. When people ask about weight-loss pills versus injections, they’re usually talking about two ways to take GLP-1 RAs. In May 2023, Novo Nordisk and Pfizer announced that pills and injections work equally well. 

Top Trending Weight Loss Medications in 2024

1. Wegovy (Semaglutide)

Wegovy is a brand name for the prescription medication Semaglutide, primarily used for weight management in adults. It belongs to a class of drugs known as GLP-1 receptor agonists. 

How Does Wegovy Work for Weight Loss?

Here’s how Wegovy works for weight loss:

Appetite Suppression: Wegovy works by mimicking a hormone called glucagon-like peptide-1 (GLP-1) that targets areas of the brain that regulate appetite and food intake. Doing so helps reduce hunger and increase feelings of fullness, leading to a reduced calorie intake.

Slowing Gastric Emptying: The medication can slow down the emptying of the stomach, contributing to increased satiety and reduced food consumption.

Impact on Blood Sugar Levels: Although primarily used for weight loss, Wegovy also affects blood sugar control. It helps lower blood sugar levels, benefiting individuals with type 2 diabetes.

Dosage and Administration: Wegovy is usually administered as a once-weekly injection under the skin (subcutaneous injection). The dose may be gradually increased over time to improve tolerability and effectiveness.

Clinical Trials and Effectiveness: Clinical trials have shown that Wegovy can lead to significant weight loss when combined with diet and exercise. The amount of weight loss varies among individuals.

How to Use Wegovy?

Wegovy is a once-a-week injection that you can administer yourself under the skin, either in your abdomen, thigh, or upper arm. You should take it on the same day every week; it doesn’t matter if you’ve eaten. 

Your healthcare provider will tell you how to give yourself the injection at home, making it more convenient for you.

Usually, the injection doesn’t hurt much because it’s injected with a very fine needle. 

Is it safe to use Wegovy for weight loss?

It is important to note that Wegovy is a prescription-only medicine. It is usually prescribed to individuals with a body mass index (BMI) of 30 or higher (obese) or 27 or higher (overweight) with at least one weight-related condition such as high blood pressure, type 2 diabetes, or high cholesterol.

Is Wegovy Available in the UK?

Wegovy is licensed for weight loss and manufactured by Novo Nordisk. It was approved by the UK Medicines and Health products Regulations Agency (MHRA) in September 2021 and became available from September 4, 2023.

Wegovy available dosages:

  • Wegovy 0.25 mg
  • Wegovy 0.5 mg
  • Wegovy 1 mg
  • Wegovy 1.7 mg 
  • Wegovy 2.4 mg

Book an online consultation with one of our experts and your Wegovy weight loss injection will be delivered at your door step.

Common Side Effects of Wegovy

The most frequent side effects of Wegovy relate to the stomach and include nausea, diarrhoea, vomiting, constipation, and stomach pain. For most individuals, these stomach-related side effects reduce or disappear within a few weeks of starting the treatment.

Does Wegovy Cause Hair Loss?

Health experts suggest that hair loss observed in patients taking Wegovy might not directly result from the medication​. Instead, it could be a response to the rapid weight loss and reduced caloric intake, which the body interprets as a stressor, leading to a shift in hair growth cycles and hair loss. 

2. Mounjaro (Tirzepatide)

Mounjaro is a newly launched weight loss medication, manufactured by Eli Lilly. It is a once-weekly injection that contains an ingredient called Tirzepatide. 

It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. It works by mimicking the action of these incretin hormones, which play a key role in regulating blood sugar levels and appetite. Here’s how it contributes to weight loss 

Appetite Suppression: Mounjaro helps reduce appetite by affecting the brain’s hunger centres, leading to reduced calorie intake.

Delayed Gastric Emptying: It slows down the emptying of the stomach, which makes you feel full for longer periods.

Enhanced Insulin Sensitivity: By improving how the body uses insulin, Mounjaro helps in better blood sugar control, which can contribute to weight management.

Increased Energy Expenditure: Some studies suggest that Mounjaro may increase the body’s energy expenditure, helping burn more calories.

Benefits of Mounjaro

Significant Weight Loss: Clinical trials have shown that Mounjaro can lead to substantial weight loss of 20% in individuals having a BMI of 30 

Improved Glycaemic Control: It helps in achieving better blood sugar levels, which is beneficial for overall health.

Cardiovascular Benefits: Mounjaro may have positive effects on cardiovascular health, reducing the risk of heart disease.

Convenient Dosing: It is administered once weekly, making it a convenient option for many patients.

Potential Side Effects

While Mounjaro is generally well-tolerated, some individuals may experience side effects, including:

Gastrointestinal Issues: Nausea, vomiting, and diarrhoea are the most common side effects.

Hypoglycaemia: When used with other diabetes medications, there is a risk of low blood sugar.

Injection Site Reactions: Redness or discomfort at the injection site.

Pancreatitis: There is a potential risk of pancreatitis, though this is rare.

3. Saxenda (Liraglutide)

Saxenda represents a significant advancement in medical weight loss solutions. As an MHRA-approved injection, it offers a novel approach to managing obesity and related health issues.

Saxenda’s active ingredient, Liraglutide, is a GLP-1 receptor agonist. This section delves into how liraglutide interacts with the body to aid weight loss and other ingredients that support its efficacy.

How Does Saxenda Work for Weight Loss?

Saxenda helps you lose weight by making you feel less hungry and fuller for longer. It slows down how quickly your stomach empties, so you end up eating less. It works like a natural hormone in your body that helps manage your blood sugar, insulin, and digestion.

Usage & Dosage

Saxenda is administered as a once-daily subcutaneous injection, typically in the thigh, abdomen, or upper arm. The dosage usually starts from 0.6 mg and gradually increases to 3mg to minimise side effects. Patients must follow the dosage instructions given by healthcare providers to achieve optimal results.

Effectiveness

Clinical trials have shown that Saxenda, when used alongside a reduced-calorie diet and increased physical activity, can lead to significant weight loss. Many users experience more pronounced weight loss in the first few months of treatment.

4. Orlistat Capsules

Orlistat capsules have emerged as a popular and effective solution for weight management. Known for its unique mechanism of action, Orlistat offers a clinically proven method to aid in weight loss. 

How Does Orlistat Help with Weight Loss?

Orlistat functions by inhibiting the action of lipase, an enzyme responsible for breaking down dietary fats in the intestine. This inhibition prevents the absorption of about one-third of the fat consumed in your diet, leading to its excretion rather than storage.

The reduction in fat absorption is a key factor in weight loss with Orlistat. Limiting the number of calories your body absorbs, Orlistat promotes a caloric deficit, which is essential for weight loss.

How much weight will I lose with Orlistat?

Research has found that combining Orlistat with a diet and exercise aimed at losing weight typically leads to more weight loss than just dieting and exercising. In fact, some individuals shed over 10% of their body weight within six months using Orlistat. 

Dosage and Administration Guidelines

Recommended Dosage

The standard dose of Orlistat is 120 mg three times a day, taken with each main meal containing fat. It’s important to adhere to the recommended dosage for optimal results.

Best Practices for Taking Orlistat

Taking Orlistat alongside a balanced, low-fat diet enhances its efficacy. Patients are advised to monitor their diet to maximize the benefits.

Potential Side Effects and Precautions

While Orlistat is generally well-tolerated, it can cause gastrointestinal side effects due to unabsorbed fats. These effects are usually temporary and manageable.

Managing and Minimising Side Effects

Adhering to a low-fat diet can significantly reduce the likelihood of experiencing side effects. Consultation with a healthcare provider is recommended for managing any persistent issues.

What is the success rate of Wegovy?

 

FAQs

What is the most effective weight loss medication?

Clinical studies have shown that 89.8% of people have lost 5% of their body weight with Wegovy weight loss injections. Hence, Wegovy is the most successful weight loss medicine so far. 

When is the best time to take Wegovy?

Wegovy should be taken once a week on the same day each week at any time of the day. You may change the day of the week you take Wegovy as long as your last dose was given 2 or more days before.

At what dose Wegovy starts working?

Everyone’s body reacts differently to the weight loss medications. However, you’ll start seeing results within 4 weeks of treatment. The starting dose of Wegovy is 0.25mg and you’ll gradually increase the dose to 1.7mg and 2.4 mg. 

How long it takes to lose weight on Wegovy?

Clinical trials have shown that Wegovy can lead to a weight loss of around 16% of your body weight, or 16-17 kg, after 68 weeks.

Where can I find Wegovy in stock?

Wegovy is currently in stock at The Care Pharmacy in the UK. All the Wegovy strengths are available at our online pharmacy in Bradford and Leeds. 

Who cannot take weight loss medications?

  • Pregnant women 
  • Breastfeeding mothers
  • Individuals with a BMI < 27 
  • People with a history of eating disorders

What is the best alternative to Wegovy?

Following are the alternatives to Wegovy:

  • Saxenda
  • Orlistat

Can I switch from Saxenda to Wegovy?

Suppose you’re currently using Saxenda and are considering switching to Wegovy. In that case, you should discuss it with your GP, medication provider, or healthcare professional first. Saxenda is a daily injection, and Wegovy is administered once a week.

What is the cost of Wegovy in the UK?

The cost of Wegovy depends on its strengths. It starts from £199 and reaches up to £299

How long does Wegovy stay in your body?

The active ingredient in Wegovy i.e. Semaglutide, has a relatively long half-life, and It stays in your body for about 7 days. However, the duration of Wegovy remains in your system depends on many factors, including the dose of Wegovy you’re on, how long you’ve used it, and even your BMI. 

 

Written by:
  • Uzma Aslam
Medically reviewed by:
  • Mohammed Ismail Lakhi
Verified by:
  • Muhammed Luqman Asghar

C0VID-19 Vaccine

The C0VID-19 vaccine works by training the immune system to recognise and fight the virus that causes C0VID-19, specifically its spike protein. C0VID-19 is a respiratory tract disease, mainly spread through respiratory droplets, aerosols, and direct contact with other people.

Price Per Dose: £ 59.99

Chickenpox Vaccine

Chickenpox is a common viral infection caused by the varicella zoster virus. This vaccine is suitable for adults and children aged between one and 65 years.

Price Per Dose: £ 74.99

Shingles Vaccine

Shingles vaccine helps to protect against getting shingles.Shingles is an infection that causes a painful rash and It’s suitable for adults aged 50 and above.

Price Per Dose: £ 219.99

Yellow Fever

Yellow fever is a viral disease caused by the yellow fever virus and transmitted through the bite of infected mosquitoes. It can lead to severe symptoms, including fever, headache, jaundice, and in severe cases, organ failure and death. Travelers visiting areas where yellow fever is endemic, particularly in tropical regions of Africa and South America, are at risk of contracting the disease. The yellow fever vaccine is a highly effective preventive measure for travelers. The typical dosing routine involves a single dose of the vaccine, which provides immunity for at least 10 years. Some countries require proof of yellow fever vaccination for entry. It is essential for travelers to get vaccinated before their journey to protect themselves and prevent the spread of the disease.

Price Per Dose: £ 69.99

Typhoid

Typhoid is a bacterial infection caused by the bacterium Salmonella Typhi. It spreads through contaminated food and water, and its symptoms include high fever, abdominal pain, and severe gastrointestinal issues. Travelers visiting regions with poor sanitation and inadequate hygiene standards are at a heightened risk of contracting typhoid. The typhoid vaccine is a crucial preventive measure for travelers. There are two types of typhoid vaccines available – the injectable vaccine and the oral vaccine. The typical dosing routine for the injectable vaccine involves a single shot. Get vaccinated against typhoid – it is essential for travelers to avoid the risk of infection and enjoy a safe and healthy journey.

Price Per Dose: £ 39.99

TBE (Tick-Borne Encephalitis)

Tick-borne encephalitis (TBE) is a viral disease transmitted to humans through the bite of infected ticks. It primarily affects the central nervous system and can lead to severe neurological symptoms, such as inflammation of the brain. Travelers visiting regions where TBE is endemic, especially during outdoor activities in wooded or grassy areas, face an increased risk of contracting the disease. The TBE vaccine provides effective protection against this potentially serious infection. The typical dosing routine involves a series of two to three doses, depending on the vaccine type used. Booster doses are also recommended to maintain immunity over time. Getting vaccinated against TBE is essential for travelers to mitigate the risk of infection and enjoy a safe and enjoyable trip.

Price Per Dose: £ 64.99

Rabies

Rabies is a deadly viral disease that affects the nervous system and is primarily transmitted through the bite of infected animals. The virus can cause a fatal infection if not treated promptly. Travelers, especially those visiting regions where rabies is prevalent and may have encounters with stray animals or wildlife, face an increased risk of contracting the disease. The Rabies vaccine is a preventive measure to protect against rabies. The typical dosing routine involves a series of doses. Typically this is given before potential exposure to the virus or after a potential exposure to ensure effective protection. Getting vaccinated against rabies is crucial for travelers to avoid the devastating consequences of this lethal infection and enjoy a safe journey.

Price Per Dose: £ 69.99

Pneumococcal (PCV/ PPSV)

The Pneumococcal vaccine, available as pneumococcal conjugate vaccine (PCV) and pneumococcal polysaccharide vaccine (PPSV), provides protection against various strains of pneumococcal bacteria. These bacteria can cause serious infections, including pneumonia, meningitis, and bloodstream infections. The PCV is primarily given to infants and young children, while PPSV is typically administered to older adults and individuals with specific medical conditions.

The typical dosing routine for PCV involves a series of doses given at specific ages during infancy. PPSV requires a single dose for most individuals, with a possible booster dose after a certain period.

Price Per Dose (PCV): £ 89.99

Price Per Dose (PPSV): £ 49.99

MMR

The MMR vaccine is a combination vaccine that provides protection against three highly contagious diseases: measles, mumps, and rubella. It is a crucial part of routine childhood immunizations. Also, it is recommended for adults who have not been vaccinated or lack immunity to these diseases. The typical dosing routine for the MMR vaccine involves two doses. The first dose is administered around the age of 12 to 15 months, and the second dose given between 4 to 6 years old. Getting vaccinated with the MMR vaccine is essential to prevent the spread of these potentially serious infections.

Ensure you and your loved ones are protected against measles, mumps, and rubella! Our experienced healthcare professionals are ready to provide you with the MMR vaccine. Come and get vaccinated with us to safeguard your health and contribute to a healthier community.

Price Per Dose: £ 44.99

Meningitis B

Meningitis B is a bacterial infection causing inflammation of the brain and spinal cord membranes. The risk of contracting it while traveling is generally low but increases in crowded settings. Be aware of the symptoms and ensure protection by getting vaccinated with us before your journey. Stay informed and stay safe during your travels.

Price Per Dose: £ 109.99

Meningitis ACWY

Meningitis ACWY is a bacterial infection that causes inflammation of the membranes surrounding the brain and spinal cord. The disease is caused by different types of bacteria, namely A, C, W, and Y. It can lead to severe health complications, including brain damage and death. Travelers, especially those visiting crowded settings like festivals, pilgrimages, or dormitory-style accommodations, may face an increased risk of contracting meningitis ACWY. To minimize the risk, vaccination is recommended, particularly when traveling to areas with active outbreaks or regions where the disease is more prevalent.

Price Per Dose: £ 49.99

Japanese Encephalitis

Japanese encephalitis is a viral infection transmitted through mosquito bites, primarily found in rural areas of Asia and the Western Pacific. The disease affects the brain and can lead to severe inflammation, resulting in neurological complications or even death. Travelers visiting or residing in regions where Japanese encephalitis is endemic, especially during the peak mosquito season, face an increased risk of contracting the virus. Taking preventive measures, such as using mosquito repellents, wearing protective clothing, and getting vaccinated, is crucial for travelers to reduce their risk of Japanese encephalitis and enjoy a safe journey.

The typical dosing for the Japanese encephalitis vaccine involves a two-dose series, with the second dose administered 28 days after the first.

Price Per Course: £ 199.99

HPV

Human papillomavirus (HPV) is a common viral infection that is primarily transmitted through sexual contact. There are multiple strains of HPV, some of which can lead to genital warts and others that can cause various cancers, including cervical, anal, and throat cancer. Travelers, especially those engaging in risky sexual behaviors, may be at risk of contracting HPV, as the virus can be prevalent worldwide. Practicing safe sex and getting vaccinated against HPV are essential preventive measures for travelers to reduce their risk of infection and the associated health complications.

Price Per Dose: £ 164.99

Hepatitis A Typhoid Combined

The Hepatitis A Typhoid combined vaccine is a convenient option for travelers seeking protection against both Hepatitis A and typhoid fever. The typical dosing schedule involves a single shot, providing immunity against both infections. This combination vaccine saves time and effort while ensuring comprehensive coverage against these travel-related diseases.

Price Per Course: £ 89.99

Hepatitis A Hepatitis B Combined

The Hepatitis A Hepatitis B combined vaccine offers protection against both Hepatitis A and Hepatitis B viruses. The typical dosing schedule involves three doses, administered at 0, 1, and 6 months. This vaccine is an excellent option for individuals seeking comprehensive protection against both hepatitis viruses in a convenient single shot.

Price Per Course: £249.99

Cholera

Cholera is a severe bacterial infection causing profuse watery diarrhea and vomiting, primarily transmitted through contaminated food and water. Traveling abroad increases the risk of contracting cholera. This is especially true in areas with poor sanitation or during outbreaks. Taking preventive measures such as getting vaccinated is crucial for travelers’ protection.

The Cholera vaccine is typically administered as two-doses, the first dose given at least one week before potential exposure to cholera and the second dose taken at least one week after the first dose.

Traveling to high-risk areas? Our trained healthcare professionals are here to help! Come and get your cholera vaccine today to ensure a safe and worry-free journey.

Price Per Course: £59.99

Hepatitis B

Hepatitis B is a viral liver infection primarily transmitted through infected blood or body fluids. Travelers and others in high-risk situations, such as unsafe medical procedures or unprotected sex, face an increased risk of contracting the virus. Vaccination against hepatitis B and adopting preventive measures are essential to safeguard against this serious infection.

The typical dosing for the hepatitis B vaccine involves a series of three doses. The initial dose is followed by a second dose at least one month later, and a third dose six months after the first dose. This vaccination provides long-term protection against hepatitis B.

Price Per Course: £149.99

Hepatitis A

Hepatitis A is a viral infection that primarily affects the liver, causing inflammation and potentially leading to symptoms like fever, nausea, and jaundice (yellowing of the skin and eyes). The virus is commonly transmitted through consuming contaminated food or water. While hepatitis A can occur anywhere, the risk of contracting it increases significantly when traveling abroad, especially to regions with poor sanitation and hygiene practices. Tourists may unknowingly consume contaminated food or water, putting them at risk of infection. It is crucial for travelers to be aware of the risk and take preventive measures, such as getting vaccinated against hepatitis A, to protect themselves during their journeys.

The typical dosing for the hepatitis A vaccine involves a two-dose series. The first dose is administered before potential exposure to the virus, and the second dose is given 6 to 18 months later to provide long-term immunity. For a booster dose, a single shot is usually recommended for ongoing protection after the initial series. Ensuring full vaccination with the recommended dosing schedule is essential to prevent hepatitis A infection and maintain immunity, especially when traveling to regions with a higher risk of the disease.

Price Per Dose: £59.99

Diptheria, Tetanus And Polio

Diphtheria, tetanus, and polio are significant infectious diseases to consider when traveling abroad. Diphtheria is a respiratory infection that causes breathing difficulties and potentially life-threatening complications. Tetanus, also known as “lockjaw,” induces severe muscle stiffness and spasms, transmitted through contaminated wounds. Polio is a viral infection that can lead to paralysis, impacting the nervous system. While vaccinations have controlled these diseases in many places, some regions may still pose risks.

Before traveling, it is recommended to get a single booster dose for diphtheria, tetanus, and polio. This reinforces immunity and reduces the risk of contracting these diseases in regions where they may still be prevalent. Ensure a safe and healthy journey by receiving the recommended booster before you travel.

Price Per Course: £39.99