Eating in a calorie deficit is often seen as the foundation of weight loss. However, many people reduce portions, eat healthier meals, and still feel stuck. When the scales do not change, it can feel confusing and frustrating.
At The Care Pharmacy, we support patients with safe, regulated weight loss treatment and clinical guidance, including weight loss injectables where appropriate. This listicle covers common reasons people are not losing weight on a calorie deficit, practical solutions to try, and how injectables may support appetite control. Get in touch to explore your options safely, or start an online consultation form to review your suitability with professional oversight.
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1) The Calorie Deficit Is Smaller Than It Looks
Many people believe they are eating less than they are. Portions can creep up over time, and small extras can add up quickly. Oils, sauces, snacks, and drinks are common sources of hidden calories.
Tracking food for a short period can highlight where calories are coming from. Measuring portions and adjusting one or two habits can often restart progress.
2) Hidden Calories From “Healthy” Foods
Some foods are healthy but calorie dense. Nuts, granola, smoothies, and nut butters can reduce your deficit if portions are too large. Even a small daily increase can slow results.
Focusing on high volume, lower calorie meals can help. Lean protein, fibre, and vegetables can support fullness while keeping calories more controlled.
3) Water Retention is Masking Fat Loss
Weight can fluctuate due to water retention. Hormones, salt intake, stress, and changes in exercise can all affect water weight. This can make fat loss harder to see on the scale.
Looking at weekly trends rather than daily weigh ins can help. Measurements and how clothes fit can also show progress more clearly.

4) You Are Losing Fat But Not Seeing It Yet
Weight loss does not always show up quickly. Some people lose fat while maintaining muscle, especially if they increase protein or start strength training. This can be positive, but it may feel slower.
Tracking measurements and progress photos can be useful. Focusing on consistency helps keep results moving in the right direction.
5) Sleep and Stress are Affecting Results
Poor sleep and high stress can increase cravings and affect hunger signals. Tiredness often leads to more snacking, especially during the evening. Stress may also cause the body to hold onto more water.
Improving sleep routines and meal structure can help. Even small changes to bedtime habits can support appetite control and energy levels.
6) Activity Levels Have Dropped Without Realising
When people eat less, daily movement can drop naturally. The body may conserve energy, leading to fewer steps and lower overall activity. This can reduce the calorie deficit over time.
Adding gentle movement can help. Walking, light strength training, and short activity breaks can support progress without intense exercise.
7) Medical Factors May Be Playing A Role
Some health conditions and medications can affect weight. Thyroid issues, hormonal changes, and insulin resistance may make weight loss harder. This does not mean progress is impossible, but it may need extra support.
Professional guidance can help identify the best next step. Getting in touch with our team can provide reassurance and structure.

8) Weight Loss Injectables Can Support Appetite Control
For some people, lifestyle changes alone may not feel enough, especially when appetite and cravings feel difficult to manage. Weight loss injectables can support fullness and appetite regulation. This can make a calorie deficit easier to maintain consistently.
At The Care Pharmacy, we provide regulated weight loss support with clinical oversight. Start an online consultation form to review your suitability or get in touch with our team for personalised guidance.
A Comparison of Weight Loss Injectables
The overview below breaks down the major weight loss injectables, including how they work, dosing frequency, and who they may suit best. It offers a simple way to compare options before discussing next steps with a clinician.
| Treatment |
How It Supports Weight Loss |
Typical Dosing |
Best For |
| Mounjaro |
Supports appetite regulation and blood sugar control |
Once weekly injection |
Patients wanting strong appetite support and structured progress |
| Wegovy |
Supports fullness and reduces appetite over time |
Once weekly injection |
Patients looking for long term weight management support |
| Saxenda |
Helps reduce appetite with daily dosing |
Daily injection |
Patients who prefer daily routine based support |
At The Care Pharmacy, we support our patients with a variety of weight loss treatments, and you can find them all on our website. Our brand new website allows you to find and buy weight loss products more easily, alongside our other services:
@thecarepharmacyukHave you had a chance to check out our brand new website yet? 👀 – Find and buy products more easily – Earn rewards on your purchases – Get automatically enrolled as an affiliate – Faster, smoother checkout – More ways to pay, including American Express & Klarna And that’s just the start… 👉 Visit the website by clicking the link in our bio and see what’s new.♬ original sound – TheCarePharmacy
9) A Plateau Does Not Mean Failure
Plateaus are common and do not mean you have failed. The body adapts over time, and routines may need adjusting. A plateau often means the plan needs refining.
Small changes can help restart progress. Tracking more closely, improving meal structure, and adding gentle activity can all support results.
Getting Weight Loss Results Back on Track
Not losing weight on a calorie deficit is frustrating, but it is often caused by hidden calories, water retention, stress, sleep disruption, or reduced activity. With the right adjustments, progress often returns and becomes easier to maintain.
Trusted, regulated weight loss support is available at The Care Pharmacy, so start an online consultation or get in touch to review your next steps with clinical oversight.
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This blog was written in collaboration with Pharmacy Mentor.
Medically reviewed by
Mohammed Lakhi
Superintendent Pharmacist