Doxycycline

£22.00

Doxycycline is a prescription antibiotic used as a daily tablet to prevent malaria in travellers to high-risk areas. Start before travel and continue for 4 weeks after leaving. Packaging and branding may differ from image shown.

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Type of medicine

Antibiotic used to prevent malaria when travelling to high-risk areas.

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Active Ingredient

Doxycycline – a tetracycline antibiotic that stops the malaria parasite from multiplying.

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Effective within

Begins protecting after 1 to 2 days of starting the course.

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Works by

Prevents malaria parasites from growing in the blood after mosquito bites.

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Side effects

May cause nausea, sun sensitivity, or stomach upset.

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Not Suitable For

Not suitable for pregnant women, children under 12, or people with severe liver disease.

Doxycycline

Doxycycline is a prescription oral antibiotic commonly used for the prevention of malaria in travellers visiting areas where the disease is prevalent. It is a tetracycline-class antibiotic that works by inhibiting the growth of malaria parasites in the bloodstream. Doxycycline is suitable for adults and children over 12 years of age and is taken as a daily tablet starting before travel, throughout the stay in the malaria area, and for four weeks after leaving. Its effectiveness, once-daily dosing, and affordability make it a widely chosen option for malaria prophylaxis, especially in regions where other medications may not be suitable. Medical supervision is important to ensure correct use and minimise side effects.

How It Works

Doxycycline prevents malaria by interfering with the ability of malaria parasites (Plasmodium species) to multiply inside red blood cells, effectively stopping the infection before it can develop.

Why Choose Doxycycline

Doxycycline offers reliable malaria prevention for most travellers and is particularly useful in areas with chloroquine or mefloquine resistance. Its once-daily dosing is convenient for travel routines, and it is often less expensive than alternative prophylactics. The medicine is also effective against other infections, which can be an advantage in some travel situations.

Important Note

Doxycycline must be taken consistently, starting before travel, during the stay, and for four weeks after leaving the malaria area. Missing doses can reduce its effectiveness. It is not suitable for pregnant women, children under 12, or individuals with certain allergies or liver or kidney problems. Protect skin from sunlight due to increased sensitivity while taking Doxycycline.

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Directions

Always follow the instructions in the patient leaflet.

  • Start taking Doxycycline 1–2 days before entering a malaria-risk area.

  • Take one tablet (usually 100mg) once daily with plenty of water, while upright.

  • Continue daily during the stay and for 4 weeks after leaving the area.

  • Avoid taking with dairy products or antacids.

  • Store below 25°C in the original packaging.

  • Keep out of sight and reach of children.

Ingredients

Excipients: Lactose monohydrate, Magnesium stearate, Microcrystalline cellulose, Sodium starch glycolate, Talc, Capsule shell ingredients (gelatin, coloring agents).

Side Effects

Common side effects may include:
Nausea or upset stomach
Diarrhoea
Sensitivity to sunlight (photosensitivity)

Serious (rare) side effects:
Severe allergic reactions (rash, swelling, difficulty breathing)
Persistent headaches or vision changes
Liver problems (yellowing of skin or eyes)

Stop using Doxycycline and seek urgent medical advice if you develop severe allergic symptoms, persistent headaches, or signs of liver problems.

Warnings

Do not use Doxycycline if you are allergic to tetracyclines or any of the ingredients. Not suitable for pregnant women, breastfeeding mothers, or children under 12 years. Use with caution in individuals with liver or kidney impairment. Avoid prolonged sun exposure or tanning beds while taking Doxycycline. Use additional protection against mosquito bites in malaria areas.

Most infections start improving within a few days, but it’s important to complete the full course even if you feel better. For acne, it may take several weeks before noticeable results appear.

Drinking alcohol while taking Doxycycline can reduce its effectiveness and may make the treatment less reliable. It’s best to avoid alcohol until you finish the full course.

Take the missed dose as soon as you remember. If it's almost time for your next dose, skip the missed one—do not take a double dose.

Some medicines, such as antacids, iron supplements, and blood thinners, can interfere with how Doxycycline works. Always check with a doctor or pharmacist before combining treatments.

Swallowing Doxycycline with plenty of water and remaining upright for at least 30 minutes helps prevent irritation or damage to the throat and oesophagus.