Atovaquone / Proguanil Tablets (Generic Malarone)

£36.00

Atovaquone/proguanil 250mg/100mg tablets are a generic alternative to Malarone for malaria prevention where recommended for your destination.

✓ 12 tablets per pack
✓ Daily course with seven days of treatment after leaving the risk area
✓ Travel assessment before supply

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Type of medicine

Antimalarial medicine used to prevent and treat malaria in areas where the disease is common.

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Active Ingredient

Atovaquone and Proguanil hydrochloride – a combination that stops the malaria parasite from growing and reproducing.

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Effective within

Begins protecting after 1 to 2 days of starting the course.

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Works by

Prevents the malaria parasite from developing in the blood, stopping infection from spreading.

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Side effects

May cause headache, nausea, stomach pain, or diarrhoea.

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Not Suitable For

Not suitable for people with severe kidney disease or those allergic to any of the ingredients.

Generic Malarone for malaria prevention

Plan protection around your itinerary with atovaquone/proguanil tablets. Our prescriber checks your destination, travel dates, health and medicines before deciding whether this option is suitable.

How many tablets will you need?

The usual adult prevention schedule is one tablet daily, starting one or two days before entering the malaria-risk area, throughout the stay and for seven days after leaving. Take with food or a milky drink.

Each pack contains 12 tablets. You may need more than one pack; the required quantity depends on your complete itinerary and prescribed start date. Include your time in the risk area and the days before and after it when discussing your supply.

Travelling soon?

Submit your assessment as early as possible and include your departure date. A short lead-in schedule does not guarantee assessment, approval or delivery before you leave. Contact the pharmacy if timing is tight.

Compare your options

Doxycycline has a different schedule, including four weeks of doses after leaving the risk area. Our prescriber can help you choose from the malaria prevention options.

No antimalarial offers complete protection. Use mosquito-bite precautions, and seek urgent medical advice for fever during or after travel, mentioning your itinerary.

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How to take the tablets

For malaria prevention, follow your prescribed daily schedule before, during and after time in the risk area. Take with food or a milky drink. Read the supplied leaflet for advice about missed doses, vomiting and diarrhoea.

Active ingredients

Each tablet contains atovaquone 250mg and proguanil hydrochloride 100mg. This product is the combination tablet. Refer to the leaflet supplied with your brand for the full list of other ingredients.

Common side effects may include:
Nausea or vomiting
Diarrhoea
Headache

Serious (rare) side effects:
Liver problems (yellowing of skin or eyes)
Severe skin reactions (rash, blistering)
Low blood cell counts

Stop taking Atovaquone and seek urgent medical advice if you develop serious symptoms or signs of liver trouble or severe allergic reaction.

Before taking atovaquone/proguanil

Tell your prescriber about kidney problems, pregnancy, breastfeeding, allergies and all other medicines. This medicine must not be used for prevention in severe kidney impairment. Malaria symptoms require urgent medical assessment, even if you have taken prevention tablets.

Take one tablet daily, starting 2 days before you travel, every day while you're in the malaria-risk area, and for 7 days after leaving. Always take with food or a milky drink.
Yes, but only if they weigh over 40kg. Always check with a doctor or pharmacist to make sure the dosage is suitable.
Take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one and continue as normal — don’t double up. Missing doses can reduce protection, so try to take it at the same time each day.
While very effective, no antimalarial offers 100% protection. It’s still important to use insect repellent, wear long sleeves, and sleep under a mosquito net in risk areas.
Yes, this is a prescription-only medicine. You’ll need to complete a short consultation to make sure it’s right for you before ordering.