What is Orlistat?
Orlistat is a weight management medication designed to support adults who are overweight or living with obesity. It works by reducing the amount of fat absorbed from the food you eat, helping to lower overall calorie intake. Unlike appetite suppressants, Orlistat acts within the digestive system rather than on the brain. It is typically prescribed for adults with a body mass index of 30 or above, or 28 and above if there are weight-related health conditions such as high blood pressure, type 2 diabetes, or high cholesterol.
Orlistat is usually taken as a capsule with meals that contain fat, up to three times per day. It is intended to be used alongside a reduced-calorie, low-fat diet and regular physical activity. It is not a replacement for healthy lifestyle changes, but a treatment that can enhance the results of a structured weight management plan when used correctly and consistently.
Orlistat as a Tool
Orlistat is not a quick solution for weight loss. It is designed to support individuals who have struggled to lose weight through diet and exercise alone. By reducing fat absorption, it can help create the calorie deficit needed for gradual and sustainable weight loss.
Because Orlistat works directly on dietary fat, commitment to a low-fat diet is essential. Eating high-fat meals while taking Orlistat can increase the likelihood of digestive side effects. One of our healthcare professionals will assess your medical history, current medications, and overall suitability before recommending treatment.
Key things to know before starting Orlistat include:
- It is taken with meals that contain fat, up to three times daily
- It works by blocking the absorption of around one third of dietary fat
- A low-fat diet is necessary to reduce the risk of digestive side effects
- It may not be suitable for people with certain digestive disorders or specific medical conditions
Knowing how Orlistat functions can help you develop realistic expectations and focus on sustainable lifestyle adjustments instead of temporary dieting.
What Is Orlistat Used For?
Orlistat is prescribed to support weight loss and weight management in adults who are overweight or obese, particularly when lifestyle changes alone have not been enough. It is generally used for:
- Weight management in adults with a BMI of 30 or higher
- Weight management in adults with a BMI of 28 or higher who have weight-related conditions such as type 2 diabetes or hypertension
By reducing fat absorption, Orlistat lowers the number of calories your body takes in from food. This can help promote steady weight loss when combined with a calorie-controlled diet and increased physical activity.
Effective weight management may positively influence general health for many individuals. Gradual weight loss may contribute to better blood pressure control, improved cholesterol levels, enhanced mobility, and increased energy levels. The aim is not just short-term weight reduction, but long-term health improvement and reduced risk of obesity-related conditions.
Orlistat may be particularly helpful for people who consume higher-fat diets and need structured support to modify eating habits while reducing calorie intake.
How Does Orlistat Work?
Orlistat works by blocking the action of lipase, an enzyme in the digestive system responsible for breaking down fat. When lipase is inhibited:
- Some of the fat consumed in meals is not absorbed into the bloodstream
- The unabsorbed fat passes through the digestive system and is excreted
- Overall calorie intake is reduced without affecting appetite directly
Because Orlistat does not suppress hunger, maintaining a balanced and portion-controlled diet remains important. Many people find that using Orlistat encourages them to make healthier food choices, as high-fat meals are more likely to cause uncomfortable digestive effects.
Common side effects are usually related to the digestive system and may include oily stools, increased urgency, flatulence, or abdominal discomfort. These effects are often more noticeable in the early stages of treatment and can be minimised by following a low-fat diet.
Orlistat and My Health
Before starting Orlistat, it is important to have a full consultation with one of our healthcare professionals. Certain conditions, such as chronic malabsorption syndromes or cholestasis, may make Orlistat unsuitable. It can also interact with some medications, so a review of your current treatment plan is essential.
Regular follow-up helps monitor progress, manage side effects, and assess whether the medication remains appropriate. In some cases, additional supplements such as fat-soluble vitamins may be recommended, as Orlistat can reduce their absorption.
Using Orlistat successfully involves more than taking capsules. It should form part of a broader health plan that includes balanced nutrition, regular physical activity, and good sleep habits. With the right support and realistic goals, Orlistat can offer structured assistance for adults seeking safe and sustainable weight management.






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