Switching from Mounjaro to Wegovy: Is It the Right Time to Switch?
Deciding when to move from Mounjaro to Wegovy depends on factors like rising costs, side effects, slowing progress, or availability.
Erectile dysfunction (ED) affects millions of men across the UK and globally, yet it’s a condition surrounded by silence and stigma. Whether you’re dealing with occasional issues or ongoing challenges, understanding the root causes of erectile dysfunction is the first step towards regaining control over your sexual health and confidence.
This comprehensive guide breaks down everything you need to know — from physical and psychological triggers to lifestyle and medication-related causes. If you’re searching for real answers, you’re in the right place.
Erectile dysfunction is defined as the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It’s more than just the occasional mishap — ED becomes a concern when it’s ongoing, frequent, and affecting quality of life or relationships.
ED is not a disease, but often a symptom of other health conditions. It’s common, particularly as men age, but it isn’t an inevitable part of ageing. Understanding its causes is crucial for effective treatment and prevention.

Poor heart health is one of the leading causes of ED. Erections depend on blood flow — and if your blood vessels are narrowed, damaged or blocked due to atherosclerosis, it can prevent adequate blood reaching the penis.
High blood pressure, high cholesterol, and clogged arteries reduce vascular efficiency, making it harder to maintain an erection.
Men with type 1 or type 2 diabetes are significantly more likely to develop ED. Elevated blood sugar damages blood vessels and nerves over time — both critical for arousal and erection.
Neuropathy (nerve damage) and reduced circulation caused by diabetes often make it difficult to get or maintain an erection.
Excess weight can lead to hormonal imbalances, lower testosterone, insulin resistance, and inflammation — all of which contribute to erectile dysfunction. Metabolic syndrome, a cluster of conditions including high blood pressure, high blood sugar, and abnormal cholesterol, increases the risk dramatically.
Low testosterone (hypogonadism) is a well-known contributor to ED. However, other hormonal imbalances like elevated prolactin, thyroid disorders, or adrenal dysfunction can also interfere with libido and performance.
Performance anxiety is real — particularly in younger men. Work stress, financial pressure, and daily life burdens can lead to chronic stress and increased cortisol levels, which suppress testosterone and reduce sexual desire.
Mental health and sexual health are deeply intertwined. Depression can lower libido, affect self-esteem, and reduce energy levels. Certain antidepressants, especially SSRIs, can also interfere with sexual function.
Intimacy issues, unresolved conflict, and lack of emotional connection with your partner can lead to psychological blocks that manifest physically. Communication breakdowns often fuel a cycle of avoidance and anxiety around sex.
Smoking damages blood vessels and restricts blood flow, making it one of the most common yet preventable causes of ED. Nicotine is a vasoconstrictor — it narrows blood vessels, including those that supply the penis.
While a drink might loosen inhibitions, chronic heavy drinking dulls the nervous system, lowers testosterone, and impairs sexual response. Long-term alcohol abuse is also associated with liver damage, nerve issues, and mental health challenges.
Lack of physical activity contributes to obesity, poor circulation, and hormonal imbalance. Regular exercise boosts blood flow, testosterone levels, and mental health — all of which are essential for sexual function.
Excessive consumption of pornography can lead to desensitisation and unrealistic expectations, resulting in reduced sexual satisfaction and difficulty performing with a real-life partner.
Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine and sertraline often lead to reduced libido, delayed ejaculation, or ED. Talk to your GP about alternatives or dosage adjustments.
Diuretics (water pills) and beta-blockers, commonly prescribed for hypertension, can interfere with erections by lowering blood flow or disrupting nerve signals.
Antihistamines, chemotherapy agents, anti-epileptic drugs, and opioids are also known to cause ED as a side effect. Always check with your healthcare provider if a new medication affects your sexual health.
You should consider seeing a doctor if:
Your GP may carry out blood tests, check testosterone levels, or refer you to a urologist or therapist, depending on the underlying issue.
Making simple adjustments can dramatically improve symptoms:
PDE5 inhibitors like Viagra (sildenafil), Cialis (tadalafil), and Levitra (vardenafil) increase blood flow to the penis and help maintain erections. These are effective for many men and are often the first line of treatment.
Testosterone replacement therapy (TRT) may be recommended if blood tests confirm low testosterone levels. This can be administered through gels, injections, or patches.
If the root of the issue is psychological, CBT (cognitive behavioural therapy) or sex therapy can be life-changing. Therapy helps tackle anxiety, confidence issues, and relationship dynamics.
For some, vacuum erection devices or penile implants may be necessary when other treatments fail. These options are safe and effective but generally used as a last resort.
Erectile dysfunction isn’t just about sex — it can affect your self-esteem, mental health, and relationships. But the good news is, it’s treatable. By identifying the underlying cause — whether physical, psychological, or lifestyle-related — you can take the first step toward recovery and confidence.
Speak to a healthcare professional, explore your treatment options, and take back control of your wellbeing.
Medically reviewed by
Superintendent Pharmacist
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