Spedra (avanafil) Tablets

Do not take Spedra:

• If you are allergic to avanafil or any of the other ingredients of this medicine 

• If you are taking “nitrate” medicines for chest pain (angina), such as amyl nitrite or glyceryl trinitrate. Spedra can increase the effects of these medicines and severely lower your blood pressure

• If you are taking medicines for HIV or AIDS such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir

• If you are taking medicines for fungal infections such as ketoconazole, itraconazole or voriconazole or certain antibiotics for bacterial infections, such as clarithromycin or telithromycin

• If you have a serious cardiac problem

• If you have had a stroke or heart attack in the last 6 months

• If you have low blood pressure or high blood pressure not controlled by medicines

• If you have chest pain (angina) or you get chest pain during sexual intercourse

• If you have a serious liver or kidney problem

• If you have a loss of vision in one eye due to not enough blood getting to your eye (non-arteritic ischemic optic neuropathy [NAION])

• If certain serious eye problems run in your family (such as retinitis pigmentosa).

• If you are taking riociguat, this medicine is used to treat pulmonary arterial hypertension (i.e., high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e., high blood pressure in the lungs secondary to blood clots). PDE5 inhibitors have been shown to increase the hypotensive effects of this medicine. If you are taking riociguat or are unsure, tell your doctor.

Do not take Spedra if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Spedra.

• Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

• The recommended dose is a 100 mg tablet, as needed. You should not take Spedra more than once a day. You could have been given the dose of one 200 mg tablet if your doctor had decided that the 100 mg dose was too weak for you, or the dose of one 50 mg tablet if your doctor had decided that the 100 mg tablet was too strong for you. Dose adjustments can also be required if Spedra is used together with certain other medicines. 

• If you are taking a medicine such as erythromycin, amprenavir, aprepitant, diltiazem, fluconazole, fosamprenavir or verapamil (‘moderate CYP3A4 inhibitors’), the recommended dose of Spedra is a 100 mg tablet, with an interval of at least 2 days between doses. 

• You should take Spedra about 30 minutes (50 mg) or approximately 15 to 30 minutes (100 mg and 200 mg) before you have sexual intercourse. Remember that Spedra will only help you to get an erection if you are sexually stimulated.

• Spedra can be taken with or without food; if taken with food, it may take longer to work.

Active Ingredient: 

Avanafil. Each tablet contains 50 mg, 100 mg or 200 mg of avanafil.

Inactive Ingredients:

• Mannitol

• Fumaric acid

• Hydroxypropylcellulose,

• Hydroxypropylcellulose low substituted

• Calcium carbonate

• Magnesium stearate

• Ferric oxide yellow (E172)

Stop taking Spedra and see a doctor straight away if you notice any of the following serious side effects, and you may need urgent medical treatment:

• an erection that will not go away (“priapism”). If you get an erection that lasts more than 4 hours, this must be treated as soon as possible or lasting damage can happen to your penis (including not being able to get erections).

• blurred vision.

• sudden decrease or loss of vision in one or both eyes.

• sudden decrease or loss of hearing (sometimes you may also feel dizzy or have ringing in your ears).

Other side effects include:

Common

• Headache

• Flushing

• Nasal congestion

Uncommon 

• Feeling dizzy

• Feeling sleepy or very tired

• Sinus congestion

• Back pain

• Hot flush

• Feeling out of breath when you exert yourself

• Heartbeat changes seen on a heart tracing (ECG)

• Increased heartbeat

• Palpitations

• Indigestion

• Blurry vision

• Raised liver enzymes

Rare

• Influenza-like symptoms

• Stuffy or runny nose

• Hayfever

• Gout

• Trouble sleeping (insomnia)

• Premature ejaculation

• Feeling strange

• Feeling unable to keep still

• Chest pain

• Serious chest pain

• Fast heartbeat

• High blood pressure

• Dry mouth

• Stomach ache

• Heartburn

• Pain or discomfort in the lower abdomen

• Diarrhoea

• Rash

• Pain in the lower back or side of the lower chest

What is Spedra?

Spedra (avanafil) is a fast-acting prescription medication used to treat erectile dysfunction (ED) by increasing blood flow to the penis, helping men achieve an erection when sexually stimulated.

How long does Spedra last?

Spedra can last for up to 4 to 6 hours after taking it, depending on the dose and individual response. However, sexual stimulation is still required for it to work.

How long does Spedra 200mg last?

Spedra 200mg, the highest recommended dose, typically lasts up to 6 hours. It provides a longer and stronger response than lower doses.

How long does Spedra take to work?

Spedra can start working as fast as 15 to 30 minutes after taking it. For best results, take it about 30 minutes before sexual activity.

Is Spedra better than Viagra?

Spedra works faster than Viagra (sildenafil). However, effectiveness can vary individually. Some men prefer one over the other based on personal experience.

Where can I buy Spedra?

Spedra is available by prescription from pharmacies in the UK, such as Care Pharmacy. Order it online from us after an online consultation.

Can you take Spedra on a full stomach?

Yes, Spedra can be taken with or without food, but a heavy or high-fat meal may delay its absorption.

How does Spedra work?

Spedra works as a PDE5 enzyme inhibitor, which relaxes blood vessels and increases blood flow to the penis during sexual activity, making it easier to achieve an erection.

How effective is Spedra?

Spedra is effective in most men with ED, especially when taken as prescribed with adequate sexual stimulation.

How long does Spedra 100mg last?

Spedra 100mg generally lasts around 4 to 6 hours, with results shown when taken about 30 minutes before sex. 

How long before sex should I take Spedra?

Take Spedra 15 to 30 minutes before sexual activity. Its quick onset makes it convenient for more spontaneous encounters compared to other ED medications.

How long is Spedra effective?

Spedra remains effective for up to 6 hours, depending on the dose. You may still achieve erections within this window if sexually stimulated.

Is Spedra available on prescription?

Yes, Spedra is a prescription-only medication in the UK. You can get it at Care Pharmacy, where our healthcare professional must assess your suitability before issuing a prescription.

Is Spedra the best for erection?

Spedra is one of the fastest-acting ED treatments available and is preferred by many for its quick onset and fewer side effects. 

Is Spedra safe to use?

Spedra is generally safe when used as prescribed. However, it may not be suitable for those with certain health conditions or those taking nitrate medications.