If you’ve been taking Mounjaro and making good progress, the thought of moving to Wegovy can bring up mixed feelings. Many people worry they’ll lose the results they’ve worked so hard for or feel as though they’re back at square one.
The truth is, switching from one medication to another doesn’t mean starting over. With the right plan and support, Wegovy can help you keep building on the progress you’ve already made.
In this blog, we’ll walk you through why some patients switch, how Wegovy compares to Mounjaro, what your first month may look like, and practical tips to make the transition smoother.
Why are Patients Switching from Mounjaro to Wegovy?
Before we dive into the changes, let’s address the elephant in the room: why are more and more people opting for Wegovy?
Let’s have a look at a few common reasons people are switching from Mounjaro to Wegovy:
- Price increases – As of 1st September 2025, Mounjaro prices in the UK have risen significantly, especially at higher doses
- Availability – Wegovy is more widely prescribed in the UK and can be easier to obtain at pharmacies.
- Response differences – Some patients simply tolerate or respond better to Wegovy.
At The Care Pharmacy, we’ll help you understand your options, review availability and costs, and support you in making the right decision.
Wegovy vs Mounjaro: What’s the difference?
WhileWegovy and Mounjaro both belong to a group called GLP-1 receptor agonists, which help regulate appetite, slow digestion and support weight loss by making you feel fuller for longer, they do act in slightly different ways. Here’s an overview on the key differences:
| Feature | Wegovy | Mounjaro |
| Ingredient | Semaglutide | Tirzepatide |
| Action | Works on GLP-1 | Works on GLP-1 + GIP |
| Dosing | Weekly, start 0.25 mg → up to 2.4 mg | Weekly, 2.5 mg → up to 15 mg |
| Side effects | Nausea, bloating, constipation, mild injection reactions | Similar stomach effects; can be stronger at higher doses |
| Effectiveness | Effective for weight loss (~15% body weight in studies) | Often greater average weight loss in trials |
What to Expect in Your First Month on Wegovy after Mounjaro?
Starting a new medication comes with its fair share of adjustments, but having an idea of what the first month on Wegovy after Mounjaro might look like can make the journey feel less stressful and easier to manage.
Week 1
- Usually starts at a low dose.
- Mild side effects (nausea, bloating, constipation) are common.
- Appetite begins to change, but weight loss is usually small at this stage.
Week 2
- Your body continues adjusting.
- Side effects often ease, though digestion can still feel slower.
- Regular meal times and eating slowly can help.
Week 3
- Appetite control becomes clearer, and cravings may reduce.
- Some patients notice early weight loss.
- Energy levels may start to improve.
Week 4
- Side effects are often easier to manage.
- Appetite feels more stable.
- Some see steady progress on the scales, while others notice changes in portion sizes and cravings first.
When to Seek Professional Help
Always reach out to your pharmacist, GP, or nurse if:
- Side effects are severe or not improving.
- You’re unable to keep fluids down.
- You’re worried about your progress or how to use the injection pen.
- We’re here to make sure you feel safe, supported, and confident.
At the Care Pharmacy, our pharmacists are trained in weight management treatments like Wegovy and Mounjaro. We can show you safe injection techniques, review your symptoms, and let you know when it’s best to see your GP for further advice.
Continuing Your Progress with Wegovy
Switching from Mounjaro to Wegovy can feel like a big step, but it doesn’t mean losing your results. Think of it as moving forward with a new tool that can continue to support your goals.
If you’re beginning Wegovy after Mounjaro and would like guidance, the Care Pharmacy team is here to help. We can answer questions about side effects, demonstrate injection technique, and provide ongoing support to help you stay on track.
Get in touch with the Care Pharmacy today to speak with a pharmacist about your weight management plan. Check out our eligibility checker to get started.
FAQs
How soon will I start seeing weight loss on Mounjaro or Wegovy?
With Mounjaro, changes often start within 3–4 weeks. Wegovy usually takes around 4 weeks, with clearer results after 12–16 weeks.
What happens if I miss a dose?
If it’s within 4–5 days, take it as soon as you remember. If longer, skip it and continue on your usual day. Don’t double up. The Care Pharmacy team can advise if you’re unsure.
Are side effects like nausea normal in the first month?
Yes, mild nausea or bloating is common as your body adjusts. Most people find these symptoms ease after the first few weeks.
Can I continue other weight loss methods alongside Mounjaro or Wegovy?
Yes. Pairing medication with a healthy diet and regular activity gives the best results.
Can I switch from Mounjaro to Wegovy safely?
Yes, if done under medical supervision. Often a short gap (around 7 days) is recommended to reduce side effects.
Will I lose weight faster on Wegovy than on Mounjaro?
Not usually. Studies show Mounjaro often produces greater average weight loss than Wegovy, though both are effective.
What should I eat in the first month of Wegovy?
Stick to smaller, balanced meals with lean protein, vegetables, and fibre. Bland foods like yogurt, eggs, or fish can help if you feel nauseous.
Are there risks of switching between GLP-1 medications?
Risks are low if the switch is managed properly. Overlapping doses can increase side effects, so always follow professional advice.
Is Wegovy available on prescription in the UK?
Yes, Wegovy is available on prescription at the Care Pharmacy, where our pharmacists provide guidance, safe dispensing, and ongoing support throughout your treatment.
