Epiduo Gel

Name: Epiduo Gel
SKU: 6994
Availability: InStock

Price range: £19.99 through £28.00

Two acne treatments in one daily gel. Epiduo combines adapalene 0.1% and benzoyl peroxide 2.5% to help clear blocked pores and inflamed spots.

✓ Antibiotic-free combination
✓ 45g and 60g pack options
✓ Online assessment by a UK prescriber

Choose your pack below. Treatment is subject to suitability.

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Quick Summary

Epiduo Gel

Type of medicine

Topical gel used to treat mild to moderate acne.

Active Ingredient

Adapalene and benzoyl peroxide – a retinoid and antimicrobial combination that unblocks pores, reduces inflammation, and targets acne-causing bacteria.

Time to results

Early improvement may appear after 1–4 weeks; progress varies.

Works by

Unclogging blocked pores, reducing skin inflammation, and killing acne-causing bacteria to help clear breakouts and prevent new ones from forming.

Side effects

Common side effects include dryness, redness, peeling, and mild burning or stinging of the skin in the treated area.

Not suitable for

Pregnancy, planned pregnancy or allergy to the ingredients. Avoid broken, eczematous or sunburned skin.

Epiduo acne gel: what makes it different?

Epiduo combines a retinoid with benzoyl peroxide, tackling blocked pores and acne-causing bacteria in one treatment. It can help with blackheads, whiteheads and inflamed spots. Unlike Differin, it contains benzoyl peroxide as well as adapalene.

Choose your pack

This page offers 45g and 60g packs of the 0.1% / 2.5% gel. Select a pack to see its price. How long it lasts depends on the area being treated; a larger pack does not mean a stronger gel.

What to expect

Use a thin layer once each evening as prescribed. Early improvement may appear after 1–4 weeks, but allow time for the treatment to work. Dryness and irritation can occur, especially at first. Do not use Epiduo during pregnancy or when planning a pregnancy.

Unsure which option fits your skin? Compare our prescription acne treatments, or read our back acne treatment guide before completing your assessment.

How should I take Epiduo?

Epiduo should be applied as a thin layer once each day to clean, dry skin, ideally in the evening before going to bed. Always follow the guidance given by your healthcare professional or refer to the patient information leaflet for full instructions. Do not apply the gel to skin that is broken, sunburned, or already irritated, and take care to avoid the area around the eyes, lips, and nose. Incorporating a daily moisturiser and sunscreen into your routine is recommended, as this treatment can make skin more sensitive to the sun. Speak to your prescriber if you have any questions about using Epiduo or if you notice any unwanted effects during treatment.

Active ingredients

Adapalene 0.1% and benzoyl peroxide 2.5%. Other ingredients are listed in the patient leaflet; check it if you have allergies.

Warnings and precautions

Do not use during pregnancy or when planning a pregnancy. Avoid broken, eczematous or sunburned skin, eyes, lips and nostrils. Avoid excessive sunlight and UV lamps. Do not combine with other retinoid or benzoyl peroxide products. Epiduo can bleach hair and fabrics.

Possible side effects

Dryness, redness, peeling and burning can occur. Ask your prescriber about persistent irritation. Stop use and seek urgent help for breathing difficulty or swelling of the face, lips or throat.

How do I store Epiduo?

Keep Epiduo stored below 25°C in a location away from direct heat and light. Ensuring the gel is kept out of reach of children and pets at all times is essential. Bathroom cabinets and areas near heat sources are not suitable storage environments for this product. Retaining Epiduo in its original packaging throughout use helps to protect it from damage and contamination. Should you have any queries regarding storage, your pharmacist or prescriber will be happy to advise.

FAQs

Epiduo frequently asked questions

Practical answers about daily use, moisturiser and what to expect from treatment.

You should apply Epiduo once daily, usually in the evening, to clean, dry skin.

Yes, using moisturiser daily alongside Epiduo can help reduce dryness and peeling.

Early improvement may appear after 1–4 weeks, but response varies. Keep to the prescribed routine and arrange a review if your acne is not improving.

Yes, you can use makeup with Epiduo, but choose non-comedogenic products and remove it gently each night.

Epiduo can cause dryness and irritation. Tell your prescriber if you have sensitive skin or eczema before starting. They may adjust how often you apply it; do not keep applying it through severe irritation.

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