Esomeprazole GR 20mg

£14.99

Esomeprazole, also known as Nexium, is a highly effective treatment designed to reduce stomach acid and provide fast, reliable relief from acid reflux and digestive discomfort. By lowering acid levels, it helps soothe irritation and protects the lining of the oesophagus, supporting longer-term digestive health and comfort.

It is also commonly prescribed alongside certain medications, such as anti-inflammatory treatments and H. pylori therapies, to help protect the stomach and reduce the risk of ulcers. If you’re considering esomeprazole or want to ensure it’s the right option for you, our healthcare professionals are available to offer tailored advice and ongoing support.

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Type of medicine

Proton pump inhibitor (PPI) used to reduce stomach acid

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Active Ingredient

Esomeprazole – a proton pump inhibitor

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Works by

Reducing acid production in the stomach to relieve symptoms of acid reflux, heartburn, and indigestion

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Effective within

Usually provides relief within 1 to 2 days of starting treatment

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Side effects

May cause headache, nausea, stomach pain, diarrhoea, or constipation

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Not Suitable For

Not for use in people with severe liver problems or known allergy to PPIs

Esomeprazole, commonly known under the brand name Nexium, is an effective treatment designed to reduce the amount of acid produced in the stomach. By lowering acid levels, it helps to relieve symptoms such as acid reflux, heartburn, and general digestive discomfort, allowing you to feel more comfortable throughout the day. It also works to protect the lining of the oesophagus from irritation caused by stomach acid and digestive enzymes, supporting longer-term digestive health.

In addition to providing symptom relief, esomeprazole is often prescribed for patients taking certain medications, including nonsteroidal anti-inflammatory drugs (NSAIDs) or treatments for H. pylori infections. In these cases, it helps to protect the stomach lining and reduce the risk of developing ulcers, making it a valuable option for both treatment and prevention.

For best results, esomeprazole should be taken as advised by your prescriber. If you are unsure whether this treatment is suitable for you or need personalised guidance, our healthcare professionals are available to support you and help you choose the most appropriate option for your needs.

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How should I take Esomeprazole?

Esomeprazole should be taken exactly as directed by your healthcare professional or according to the instructions in the patient information leaflet. It is usually taken once daily, preferably in the morning before food, unless advised otherwise.

Swallow the tablet or capsule whole with a glass of water and do not crush or chew it, as this can affect how the medicine works. If required, some formulations can be dispersed in water, but always check the leaflet first. Take it consistently for best results, and if you miss a dose, take it when you remember unless it is close to your next dose.

What ingredients are in Esomeprazole?

Esomeprazole contains the active ingredient esomeprazole, a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach.

In addition to the active ingredient, it may contain inactive components such as sucrose, maize starch, magnesium stearate, and coating agents. These help protect the medicine and ensure it is delivered effectively.

Always check the patient information leaflet supplied with your medication for a full and accurate list of ingredients, especially if you have allergies or sensitivities. If you are unsure, speak to your pharmacist before taking Esomeprazole.

Warnings and precautions

Esomeprazole may not be suitable for everyone. Speak to a healthcare professional before using it if you have liver problems, unexplained weight loss, difficulty swallowing, or persistent stomach pain, as these may require further investigation.

Long-term use of Esomeprazole may be associated with risks such as low magnesium levels, vitamin B12 deficiency, or an increased risk of bone fractures. Always use the lowest effective dose for the shortest duration needed.

If you are taking other medications, including clopidogrel, antifungals, or HIV treatments, inform your doctor or pharmacist, as interactions may occur. If you are pregnant or breastfeeding, seek medical advice before use.

What are the side effects of Esomeprazole?

Esomeprazole may cause side effects, although many people use it without significant problems. Common side effects can include headache, abdominal pain, diarrhoea, constipation, or nausea. These are usually mild and improve over time.

Less commonly, some people may experience dizziness, dry mouth, or skin reactions. Rare but more serious side effects can include severe allergic reactions, liver problems, or persistent gastrointestinal symptoms.

If you experience severe or unusual symptoms, such as swelling of the face or throat, difficulty breathing, or ongoing stomach pain, seek medical advice promptly. Always use Esomeprazole as directed and consult a healthcare professional if you have concerns.

How do I store Esomeprazole?

Store Esomeprazole at room temperature in a cool, dry place, away from direct heat and sunlight. Keep the medication in its original packaging to protect it from moisture and light.

Keep out of sight and reach of children and do not use after the expiry date printed on the packaging. If you have any unused medication, speak to your pharmacist about safe disposal.

Most people tolerate Esomeprazole well. Common side effects include headache, diarrhoea, constipation, nausea, and stomach pain. If you experience severe side effects such as rash, dizziness, or difficulty breathing, seek medical help immediately.
Some people start feeling relief from heartburn and acid reflux symptoms within 1–2 days, but it may take up to 4 weeks for full effect. Continue taking it as directed, even if you feel better.
Some medicines can interact with Esomeprazole, including certain antifungal drugs, HIV medicines, and blood thinners. Always tell your doctor or pharmacist about any other medications or supplements you are taking.
Take one tablet once daily, preferably in the morning before eating. Swallow the tablet whole with water — do not crush or chew it. Always follow the dosage instructions provided by your doctor or pharmacist.
Esomeprazole 20mg is used to treat conditions caused by excess stomach acid, such as acid reflux, heartburn, indigestion, and gastro-oesophageal reflux disease (GORD). It helps reduce the amount of acid your stomach produces, providing relief from discomfort and preventing irritation of the oesophagus.