Epiduo Price Comparison UK: 45g and 60g Gel
Compare standard Epiduo 0.1%/2.5% gel prices for 45g and 60g packs, including delivery, prescription fees and sensible pack-size checks.
Duac prices should be compared by both ingredient strength and pack quantity. In our UK sample checked on 8 October 2026, a 30g pack with clindamycin 1% and benzoyl peroxide 5% cost £29.99 from The Care Pharmacy, £30 from Boots Online Doctor and £18.49 from The Family Chemist before separate delivery charges. A 3% benzoyl peroxide pack is a different strength, and a larger order must fit your prescribed course and expiry date.

For a single 30g pack of 1%/5% gel, The Care Pharmacy’s standard-delivery example is £33.98. Boots lists £30.00 with free standard delivery. The Family Chemist’s medicine price is lower, but check which of its delivery services applies before treating a calculated total as your final quote.
The Care Pharmacy also lists a 60g pack of the same strength at £43.99, qualifying for its free standard delivery. A larger tube has a lower cost per gram, but that is useful only when the quantity is clinically appropriate and can be used within the dispensing expiry.
These are the same ingredient strengths, with the supplied amount shown explicitly. Two 30g tubes contain 60g in total, but are kept visible as two separate containers.
| Provider | Quantity | Medicine price |
|---|---|---|
| The Care Pharmacy | 30g | £29.99 |
| The Care Pharmacy | 60g | £43.99 |
| Boots Online Doctor | 30g | £30.00 |
| The Family Chemist | 30g | £18.49 |
| The Family Chemist | 2 x 30g | £36.49 |
This is a provider sample checked on one date. It is not a complete UK cheapest-price claim or a clinical ranking. No introductory code, membership saving or loyalty points have been deducted.
The lower benzoyl peroxide concentration is not the same product as the 5% gel above. Both contain clindamycin 1%, but the other ingredient differs. The Care Pharmacy prices in this guide cover its listed 1%/5% gel.
| Provider | Quantity | Medicine price |
|---|---|---|
| Dr Fox | 30g | £17.95 |
| Dr Fox | 60g | £34.10 |
| Boots Online Doctor | 30g | £30.00 |
| The Family Chemist | 30g | £18.49 |
| The Family Chemist | 2 x 30g | £36.39 |
Do not choose a strength because another table looks cheaper. Confirm the exact preparation your prescriber recommends. The order of the percentages can vary in a listing, so check which number belongs to clindamycin and which to benzoyl peroxide.
The Care Pharmacy’s standard delivery is £3.99, free on orders over £40.00. No separate prescription charge was displayed with its checked Duac prices. Boots advertises free standard delivery for its acne service.
Dr Fox adds £2.00 to its £17.95 30g 3% pack for the prescription and £2.90 for delivery, giving £22.85. Its 60g 3% pack falls into the £3.00 prescription-fee band and totals £40.00 with standard delivery.
| Pack and provider | Medicine | Separate fees | Total |
|---|---|---|---|
| 1%/5% 30g: The Care Pharmacy | £29.99 | £3.99 | £33.98 |
| 1%/5% 60g: The Care Pharmacy | £43.99 | Standard delivery included | £43.99 |
| 1%/5% 30g: Boots Online Doctor | £30.00 | Standard delivery included | £30.00 |
| 1%/3% 30g: Dr Fox | £17.95 | £4.90 | £22.85 |
The Family Chemist publishes £2.99 standard delivery below its over-£20.00 free-delivery threshold, and a separate free delivery service for fridge medicines. Its £18.49 pack would total £21.48 if the standard charge applies. Confirm the applicable service for Duac; that calculation is not a checked basket quote. Its two-tube offers exceed the published standard-delivery threshold.

Duac is not a gel to buy indefinitely in bulk. The Duac 1%/5% prescribing information gives a two-month shelf life after dispensing, when the pharmacy prepares and supplies the medicine. This is not a two-month clock that starts only when you first open the tube.
Follow the pharmacy’s dispensing label and the pack instructions. Opening a second tube later does not reset a dispensing expiry. That point matters if a multi-pack offer looks attractive or you still have an older tube at home.
Continuous treatment should not exceed 12 weeks. Your clinician decides the course and review plan, while each supplied pack has its own expiry. A course and a tube therefore have different timelines; do not assume a single purchase is automatically suitable for the whole course.
Keep the dispensing and expiry dates somewhere you can check easily. Ask the pharmacist if either is unclear. Do not carry on using expired gel because there is some left or because replacing it feels wasteful.
The Care Pharmacy’s 30g medicine price works out at approximately £1.00 per gram. The 60g medicine price is about £0.73 per gram. Including standard delivery makes the 30g example about £1.13 per gram, while the qualifying 60g order remains about £0.73.
Those figures describe the quantity supplied, not how much you should apply or a guaranteed duration. Treating one facial area can use a different amount from treating larger affected areas. Ask the prescriber what quantity fits your plan before comparing unit prices.
Two 30g tubes and one 60g tube can be compared by total grams, but container format and dispensing expiry still matter. Two tubes do not necessarily last twice as many usable months. They may be dispensed together with the same expiry instructions.
If the budget is difficult, explain that early. A clinician can review the plan, quantity or treatment choice. Buying extra antibiotic gel or extending the course yourself is not a sensible way to make the cost per gram look better.
Duac contains an antibiotic, so an ongoing plan needs more than repeat supply. NICE acne guidance discusses review and the risk of antibiotic resistance, when bacteria become less sensitive to antibiotics. Your prescriber should consider what happens after the course, rather than leaving you to reorder indefinitely.
Do not assume an automatic refill is appropriate simply because the provider offers one. A new assessment may be needed, or a different longer-term treatment may be recommended. Tell the clinician how often you actually used the gel and whether side effects caused breaks.
For an ingredient-choice comparison, see our Epiduo and Duac guide. That clinical question is separate from comparing the cost of an appropriate Duac prescription.
Duac can cause dryness and irritation and bleach hair or fabrics. Tell the prescriber about previous bowel inflammation, antibiotic-related diarrhoea, allergies, pregnancy or breastfeeding. Discuss other acne products before combining them with treatment.
Stop and seek medical advice for significant diarrhoea or abdominal cramps, or troublesome severe skin irritation. Call 999 for breathing difficulty or swelling of the tongue or throat. Keep these symptoms separate from ordinary mild dryness.
After dispensing, the 1%/5% prescribing information says not to store above 25°C. Follow the pharmacy label rather than assuming all stages of the supply chain use the same storage conditions. Check the dispensing pharmacy through the GPhC register; a bargain listing cannot replace appropriate prescribing checks.
Read the Duac patient leaflet supplied with your treatment. If acne is deep, painful, scarring or affecting your wellbeing, seek medical advice rather than simply ordering more gel.
No. Match the benzoyl peroxide strength and clindamycin strength to your prescribed treatment. A cheaper entry for another strength is not an identical quote.
Do not assume that. The 1%/5% product has a two-month shelf life after dispensing. Follow each dispensing label; opening later does not automatically extend that date.
Discuss the next step with your prescriber. Continuous Duac treatment should not exceed 12 weeks, and the antibiotic component needs an appropriate review plan.
The Care Pharmacy can assess whether its Duac 1%/5% gel is suitable for your acne. Explain previous treatment, current skincare and side effects so a prescriber can consider a course and quantity that fit your needs.
Mohammed Ismail Lakhi MPharm
Superintendent Pharmacist at The Care Pharmacy
GPhC Registration Number: 2072815
The Care Pharmacy is led by Superintendent Pharmacist Mohammed Ismail Lakhi MPharm. The pharmacy assesses individual suitability before prescribing or supplying prescription treatment. Your own clinician can explain how general guidance applies to your health, medicines and treatment plan.
Medically reviewed by
Superintendent Pharmacist
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